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Honeycomb Films of Cellulose Azide: Molecular Structure and Formation of Porous Films
journal contribution
posted on 2013-01-15, 00:00 authored by William
Z. Xu, John F. KadlaDevelopment of value-added micropatterned porous materials
from
naturally abundant polymers, such as cellulose, are of growing interest.
In this paper, regioselectively modified amphiphilic cellulose azide,
3-O-azidopropoxypoly(ethylene glycol)-2,6-di-O-thexyldimethylsilyl cellulose, with different degrees
of substitution (DS) and degrees of polymerization (DP) of the poly(ethylene
glycol) (PEG) side chain, was synthesized and employed in the formation
of honeycomb-patterned films. With the variation of the DP and/or
DS, the amphiphilicity of the polymer and the pore size of the formed
films changed accordingly. It was found that amphiphilicity of the
cellulose azide played a significant role in the formation of honeycomb
films. Balanced amphiphilicity was of particular importance in the
formation of uniform honeycomb films. Via the CuI-catalyzed
alkyne–azide [2 + 3] cycloaddition reaction, fluorescent avidin
and quantum dots were attached to the films. By means of confocal
microscopy, it was confirmed that the functional azido group was preferentially
allocated inside the pores. This provides a platform for the development
of advanced honeycomb materials with site-specific functionalities,
such as biosensors.