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Highly Sensitive and Reusable Membraneless Field-Effect Transistor (FET)-Type Tungsten Diselenide (WSe2) Biosensors
journal contribution
posted on 2018-05-16, 12:19 authored by Hae Won Lee, Dong-Ho Kang, Jeong Ho Cho, Sungjoo Lee, Dong-Hwan Jun, Jin-Hong ParkIn
recent years when the demand for high-performance biosensors has been
aroused, a field-effect transistor (FET)-type biosensor (BioFET) has
attracted great interest because of its high sensitivity, label-free
detection, fast detection speed, and miniaturization. However, the
insulating membrane in the conventional BioFET, which is essential
in preventing the surface dangling bonds of typical semiconductors
from nonspecific bindings, has limited the sensitivity of biosensors.
Here, we present a highly sensitive and reusable membraneless BioFET
based on a defect-free van der Waals material, tungsten diselenide
(WSe2). We intentionally generated a few surface defects
that serve as extra binding sites for the bioreceptor immobilization
through weak oxygen plasma treatment, consequently magnifying the
sensitivity values to 2.87 × 105 A/A for 10 mM glucose.
The WSe2 BioFET also maintained its high sensitivity even
after several cycles of rinsing and glucose application were repeated.