High-MW Gab1 is expressed in the heart.

<p>Expression patterns of A) Gab1 and B) high-MW Gab1 protein in mouse tissues. Following immunoprecipitation with A) anti-Gab1 or B) anti-high-MW Gab1 serum, expression of Gab1 was examined by immunoblotting analysis with anti-Gab1 antibody. The high-MW Gab1 is expressed in heart (arrowheads), and the low-MW Gab1 is commonly expressed (arrow). SHP2 was examined as a loading control. Results are representatives of three independent experiments.</p>