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Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil

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posted on 2018-01-17, 02:52 authored by Nara Rubia de Freitas, Sheila Araújo Teles, Karlla Antonieta Amorim Caetano, Marcos Andre de Matos, Megmar Aparecida dos Santos Carneiro, Noemi Rovaris Gardinali, Marcelo Alves Pinto, Regina Maria Bringel Martins

Abstract INTRODUCTION: Prevalence of hepatitis E virus (HEV) infection and associated factors were investigated in rural settlements in Central Brazil. METHODS: A total of 464 settlers were interviewed, and serum samples were tested for anti-HEV IgG/IgM. Positive samples were tested for HEV RNA. RESULTS: Sixteen participants (3.4%; 95% CI 2.0-5.7) were positive for anti-HEV IgG. None was positive for anti-HEV IgM. HEV RNA was not detected. Dwelling in a rural settlement for >5 years was associated with HEV seropositivity. CONCLUSIONS: The results revealed the absence of acute infection and a low prevalence of previous exposure to HEV.

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    Revista da Sociedade Brasileira de Medicina Tropical

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