Fig 2.TIF (1.01 MB)
HCT116 cells were treated with different doses of API (0.5, 1, 5, and 10 μM) for 48 h, harvested and stained with propidium iodide and subjected to flow cytometry.
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posted on 2016-09-29, 17:34 authored by Anilkumar C. Nirvanappa, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Hanumappa Ananda, Alexey Yu Sukhorukov, Muthu K. Shanmugam, Mahalingam S. Sundaram, Siddaiah Chandra Nayaka, Kesturu S. Girish, Arunachalam Chinnathambi, M. E. Zayed, Sulaiman Ali Alharbi, Gautam Sethi, Basappa, Kanchugarakoppal S. RangappaHistogram obtained indicated the accumulation cells in sub-G1 phase.
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κB phosphorylationAPIIFNtargets NF -κBfactor kappa BNF -κB bindingOxazines Target NF -κBbowel disease modelInflammatory Bowel DiseaseHCT 116 cellsinflammation bowel diseaseDNAflow cytometry analysisoxazineVivo Aberrant activationNF -κBdextran sulphate sodium-induced IBD mice modelcolorectal cancer cell linesTNFILNF -κB luciferase expression
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