Granulosa cells co-incubated with exosomes showed reduction in ROS level under oxidative stress or normal conditions compared to control ones.

The ROS level (A) was measured under normal or oxidative stress conditions in granulosa cells co-incubated with exosomes released under normal (NormalExo) or stress (StressExo) conditions compared to groups cultured without exosomes. The ROS fluorescence intensity analysis (B). Data are mean ± SEM from four independent biological replicates. Bars with different letters showed statistically significant differences (p < 0.05).