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Biomarker Benchmark - GSE19804

Version 6 2016-03-17, 23:08
Version 5 2016-03-17, 22:19
Version 4 2016-03-17, 17:49
Version 3 2016-02-23, 23:36
Version 2 2016-02-04, 22:25
Version 1 2016-02-02, 21:58
dataset
posted on 2016-03-17, 23:08 authored by Anna GuyerAnna Guyer, Stephen PiccoloStephen Piccolo

[NOTICE: This data set has been deprecated. Please see our new version of the data (and additional data sets) here: https://osf.io/mhk93 ]


"Although smoking is the major risk factor for lung cancer, only 7% of female lung cancer patients in Taiwan have a history of cigarette smoking, extremely lower than those in Caucasian females. This report is a comprehensive analysis of the molecular signature of non-smoking female lung cancer in Taiwan."

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE19804

We have included gene-expression data, the outcome (class) being predicted, and any clinical covariates. When gene-expression data were processed in multiple batches, we have provided batch information. Each data set is organized into a file set, where each contains all pertinent files for an individual dataset. The gene expression files have been normalized using both the SCAN and UPC methods using the SCAN.UPC package in Bioconductor (https://www.bioconductor.org/packages/release/bioc/html/SCAN.UPC.html). We summarized the data at the gene level using the BrainArray resource (http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/20.0.0/ensg.asp). We used Ensembl identifiers. The class, clinical, and batch data were hand curated to ensure consistency ("tidy data" formatting). In addition, the data files have been formatted to be imported easily into the ML-Flex machine learning package (http://mlflex.sourceforge.net/).

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