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GFP-Rab11A intracellular movement in DMSO treated A549 cells.

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posted on 2019-11-06, 16:32 authored by Amar BhagwatAmar Bhagwat, Seema LakdawalaSeema Lakdawala
TIFF series of diSPIM datasets, fused and deconvolved, from A549 GFP-Rab11A cells treated with DMSO (control). Each TIFF file is a full cell volume of 50 planes, with isotropic resolution of 330nm, each .zip file is an independent replicate with at least 1 or 2 cells analyzed for 3D tracking of cytoplasmic foci with 500 time stamps. The data from these cells correspond to Supplementary Movie 3 and analysis of these movies provided data presented in Figure 3 and Supplementary Figure 4.

Supplementary Movie 3: A549 GFP-Rab11A cells under control treatment (DMSO).

Figure 3: Motion Dynamics of Rab11A under the effect of cytoskeletal depolymerizing drugs.

Supplementary Figure 4: Impact of skeletal depolymerizing drugs on the transport of Rab11A.

Funding

Visualizing Influenza Viral RNA Packaging

National Institute of Allergy and Infectious Diseases

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Visualization of Influenza Viral RNA Assembly

National Institute of Allergy and Infectious Diseases

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The Role of Pathogen-Environment Interactions in the Pandemic Potential of Influenza

National Institute of Allergy and Infectious Diseases

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Intramural research program of the National Institute of Biomedical Imaging and Bioengineering (NIBIB)

American Lung Association Biomedical Research Award (RG-575688)

New Initiative Award (KA2018-98552) from the Charles E. Kaufman Foundation, a supporting organization of The Pittsburgh Foundation

History

Select an IC:

  • AI - National Institute of Allergy and Infectious Diseases (NIAID)

Is this associated with a publication?

  • Yes

I confirm there is no human identifiable information in this dataset.

  • Yes

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