ol9b00193_si_001.pdf (11.44 MB)
Fungal Biosurfactants from Mortierella alpina
journal contribution
posted on 2019-02-21, 16:48 authored by Florian Baldeweg, Paul Warncke, Dagmar Fischer, Markus GresslerThe zygomycete Mortierella alpina is a well-known
producer of polyunsaturated fatty acids in the food industry. Two
series of its secondary metabolites are reported: Malpinins, a family
of amphiphilic acetylated hexapeptides, were chemically characterized
and serve as natural emulsifiers during lipid secretion. Additionally,
hydrophobic cyclopentapeptides, malpibaldins, were structurally elucidated
by NMR experiments, and their absolute stereochemistry was elucidated
through chemical derivatization and synthesis. This work highlights
lower fungi as a novel reservoir for natural products.