Functional recovery evaluated using five toe spread analysis.

(A) Photographs of five toe spread at postoperative day 36 in five different groups of mice—normal (pre-transected), negative control (PBS only), EiPSC, 129 ESC and C57BL/6 (B6) group. (B) Cumulative graph of the four different groups expressed as a percentage of five toe spread recovery over pre-transection measurements postoperatively. The statistical data comparing EiPSC, 129 ESC and B6 ESC groups between negative control showed a mean±SEM which was significant (P value of < 0.0001, one-way ANOVA) at each time point.