am7b12364_si_001.pdf (1.72 MB)
Fluoropolymer-Based Flexible Neural Prosthetic Electrodes for Reliable Neural Interfacing
journal contribution
posted on 2017-11-29, 00:00 authored by Yong Hee Kim, Jongkil Park, Ho Koo, Min Sun Kim, Sang-Don JungWe
covalently bound fluoropolymer (FP) films by plasma treatment followed
by thermal pressing at temperatures below their melting point and
fabricated an adhesion-metal-free flexible gold electrode array entirely
encapsulated by the FP film, excepting the active electrode openings.
The fabricated device was chemically resistant and was modified to
have a lower impedance and efficient charge injection capability.
The fabricated device was evaluated in vivo in rats and was confirmed
to record the epidural epileptiform activity induced by chemical administration.
The chemically inert nature of FPs and the gold electrode is expected
to facilitate reliable neural interfacing without abiotic issues.
Plasma treatment-induced covalent binding of FP films can also be
utilized in a variety of applications requiring durability, such as
implantable biosensors and sensor platforms operating under chemically
harsh environments, including humid conditions.