Figure S7: Differential metabolite abundances and enzyme associated gene expression in the pyrimidine metabolism pathway between control and aposymbiotic tsetse from Unravelling the relationship between the tsetse fly and its obligate symbiont <i>Wigglesworthia</i>: transcriptomic and metabolomic landscapes reveals highly integrated physiological networks

Metabolite data was derived from bacteriome specific metabolomic analysis. Differential enzyme transcription was derived from transcriptomic data from whole guts of control and aposymbiotic flies. Enzymes are represented as rectangles and defined by their KEGG Enzyme ID numbers and metabolites/cofactors are represented as circles and are labeled with metabolite names. Enzyme and metabolite symbols are colored to reflect their increased (blue) or decreased (red) expression (for enzymes) or abundance (for metabolites). Light blue/red symbols represent changes in abundance approaching significance (p-value between 0.1 - 0.05). Green symbols reflect <i>Wigglesworthia</i> derived enzymes/metabolites. Numerical representation of metabolite data is in Table S7 and enzyme gene expression data is in Table S9.