Figure S1. Gene orthology analyses of nodal and pitx from Embryonic chirality and the evolution of spiralian left–right asymmetries

Maximum likelihood phylogenetic trees of N. anomala nodal (a) and O. fusiformis pitx, L. ruber pitx and P. caudatus pitx genes (b). Replicate bootstrap values were calculated with the autoMRE option in RAxML. The model of protein evolution used in both trees is LG+G+I. Sequences analysed in this study are highlighted in red.