Figure12.tiff (22.89 MB)
Figure 12. SOX17 depletion by AID with TIR1-DD.
figure
posted on 2019-07-25, 15:52 authored by Merrick Pierson SmelaMerrick Pierson Smela, Anastasiya Sybirna, M. Azim SuraniFigure 12. SOX17 depletion by AID with TIR1-DD. SOX17-AID-Venus cells with PB-TIR1-DD were induced to form PGCLCs and treated with IAA and Shield1 from the start of the induction. After four days, EBs were fixed, sectioned, and stained using antibodies against GFP, SOX17, and KLF4. The untreated sample contains many SOX17 positive PGCLCs, whereas only a few are visible in the treated sample. Scale bar is 50 µm.
Funding
Core funding for Wellcome Trust / Cancer Research UK Gurdon Institute
Cancer Research UK
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