Figure 4RR.tif (445.79 kB)
Fig 4 Qrfp-/- mice exhibited increased anxiety-like behavior and decreased wakefulness in the early hours of the dark period.
figure
posted on 2016-10-20, 01:17 authored by Kitaro OkamotoKitaro Okamoto, Miwako Yamasaki, Keizo Takao, Shingo Soya, Monica Iwasaki, Koh Sasaki, Kenta Magoori, Iori Sakakibara, Tsuyoshi MiyakawaTsuyoshi Miyakawa, Michihiro Mieda, Masahiko Watanabe, Juro Sakai, Masashi Yanagisawa, Takeshi SakuraiTakeshi SakuraiA, Elevated plus maze test. Qrfp-/- mice showed fewer entries into the open arms, and spent a shorter time in the open arms.
B, Open field test. Qrfp-/- mice showed decreased spontaneous horizontal and vertical activities. Stereotypic behavior and time spent in the central area were not
significantly different between Qrfp-/- mice and wild type mice.
significantly different between Qrfp-/- mice and wild type mice.
C, Decreased wakefulness time of Qrfp-/- mice in early hours of dark period. Hourly amounts of each sleep state (mean ± SE) are plotted over 24 h for control littermates (n = 10) and Qrfp-/- mice (n = 10). Data for the dark and light phases are displayed on light gray and white backgrounds, respectively. Upper, Wakefulness time. Middle, NREM sleep time. Lower, REM sleep time.
