2016-11-23T09:32:42Z (GMT) by Benjamin Laenen
<p>Figure 2. The impact of purifying selection differs between genes with and without ASE in <i>C. grandiflora. </i>The estimated proportion of mutations in each <i>N<sub>e</sub>s </i>bin of the distribution of negative fitness effects (DFE) is shown, with whiskers corresponding to 95% confidence intervals. The panels show the DFE for nonsynonymous sites (0-fold degenerate sites) (A), for introns (B), for promoter regions 500 bp upstream of the transcription start site (C) and for 3'-UTRs (D). Significance levels for comparisons of ASE and control genes, that were also amenable to analysis of ASE, are indicated by asterisks (*: P-value ≤ 0.05, ** P-value ≤ 0.01). These results are based on the population sample and the one-epoch model.</p>