Fig2.pdf

Figure 2. The impact of purifying selection differs between genes with and without ASE in C. grandiflora. The estimated proportion of mutations in each N_es bin of the distribution of negative fitness effects (DFE) is shown, with whiskers corresponding to 95% confidence intervals. The panels show the DFE for nonsynonymous sites (0-fold degenerate sites) (A), for introns (B), for promoter regions 500 bp upstream of the transcription start site (C) and for 3'-UTRs (D). Significance levels for comparisons of ASE and control genes, that were also amenable to analysis of ASE, are indicated by asterisks (*: P-value ≤ 0.05, ** P-value ≤ 0.01). These results are based on the population sample and the one-epoch model.