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Far-UV CD spectra of native GAPDH and GAPDH treated with 32 μM of piceatannol at room temperature for 50 and 100 min of incubation.

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posted on 2018-01-03, 18:39 authored by Joanna Gerszon, Eligiusz Serafin, Adam Buczkowski, Sylwia Michlewska, Jakub Antoni Bielnicki, Aleksandra Rodacka

The data are expressed as molar residue ellipticity.

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    oxidative modificationsnucleophilic cysteine residueglyceraldehyde -3-phosphate dehydrogenase Glyceraldehyde -3-phosphate dehydrogenaseGAPDH aggregation11 ligand binding positionsITCGAPDH piceatannol blocks cysteine residuepiceatannol decreases GAPDH activityreactive cysteine residue

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