Fig 7.tif (523.13 kB)
Expression of IGF1R in mouse livers with H19 knockout on different parental alleles.
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posted on 2017-11-03, 17:33 authored by Chad Pope, Stephanie C. Piekos, Liming Chen, Shashank Mishra, Xiao-bo Zhong(A) RNA expression was determined by RT-PCR in mouse livers at ages 5, 10, 15, 20, 30, and 60 days after birth (n = 4 per group). (B) Protein expression was determined by Western blot for IGF1R for mice at ages 5, 10, 15, 20, and 60 days after birth. Lanes 1–3 indicate wild type (H19+/+) individuals and lanes 4–6 indicate H19M-/P+ individuals. Values are represented as mean ± S.D.
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insulin-like growth factor 2drug metabolizing enzymesmouse liver postnatal maturation H 19 RNAmiR -675 expressionH 19 knockout mouse modelliver developmentliver maturationH 19β- catenin proteincell proliferationIGF 1R increasesIGF 1R expressionadult plasma proteinP 450 expression patternsrolecytochrome P 450insulin-like growth factor 1 receptorinsulin growth factorH 19 expression
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