Exon expression pattern of concussion predicts clinical diagnosis.

A. Hierarchical clustering shows pattern of separation between concussed and controls based on expression of 29 exons (x-axis) B. Principle component analysis plot shows the exon expression patterns separate due to concussion status. C Results of testing SVM generated model of 25 exons (Table 2) on testing data set, using a diagnosis of PCS/ concussion as the positive call. Note the accuracy was 86%, sensitivity 80% and specificity of 89%.