Evolutionary dynamics in Aspergillus niger fitness landscape

Aspergillus niger landscape. Population size is 1,000. Mutation rate is 0.01. Mutations can only move an organism between neighboring genotypes. Area of red circles on genotypes is proportional to fraction of population that has that genotype.

Data is from Franke J, Klözer A, de Visser JAGM, Krug J (2011) Evolutionary Accessibility of Mutational Pathways. PLoS Comput Biol 7(8): e1002134.