pone.0211462.g002.tif (840.37 kB)
Eq upregulates protein expression of adhesion molecules in HUVECs.
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posted on 2019-01-30, 19:01 authored by Fumitake Ito, Taisuke Mori, Yosuke Tarumi, Hiroyuki Okimura, Hisashi Kataoka, Yukiko Tanaka, Akemi Koshiba, Jo KitawakiHUVECs were treated with various estrogens as described in Fig 1. (A) E-selectin, (B) ICAM-1, (C) P-selectin, and (D) VCAM-1 protein levels were quantified by EIA. Data are expressed as the mean ± SEM of four experiments. *P < 0.05 vs. vehicle alone.
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intercellular adhesion moleculeequilin treatmentNF -κB activationadhesion molecules E-selectinadhesion moleculesprotein expression levelsERatherosclerosiequine estrogen increases monocyte-endothelial adhesionE 2 treatmentestrogen-replacement therapypolymerase chain reactionHUVECConjugated equine estrogenNF -κB subunit p 65U 937 monocytoid cellsE 2NF -κB proteinsEquilin
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