U537346.pdf (3.04 MB)
Enantoioselective reactions of some optically active phosphines.
thesis
posted on 2015-11-19, 08:45 authored by G. F. JayThe enantioselective chlorination of alcohols by the menthyldipheny1-phosphine/carbon tetrachloride reagent previously reported in the literature was investigated and quantified. Further examples were found. A new enantioselective reaction of menthyldipheny1phosphine/carbon tetrachloride was discovered. This was the synthesis of aziridines by ring closure of ? amino alcohols. Other optically active phosphines in conjunction with carbon tetrachloride were found to react in a similar manner to menthy1dipheny1phosphine/carbon tetrachloride with a variety of ? amino alcohols. Menthy1dipheny1phosphine was found to react enantioselectively with a ? amino alcohol in the presence of chlorine.
History
Date of award
1987-01-01Author affiliation
ChemistryAwarding institution
University of LeicesterQualification level
- Doctoral
Qualification name
- PhD