Enantioselective total synthesis of β-zearalenol from (<i>s</i>)- propylene oxide

<p>The total synthesis of 14-membered resorcylic acid macrolide, β-Zearalenol was accomplished starting from commercially available enantiomerically pure propylene oxide and methyl 2,4-dihydroxy-6-methylbenzoate using Grignard reaction, Asymmetric dihydroxylation, Yamaguchi macrolactonization and RCM as key steps.</p>