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Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy
journal contribution
posted on 2017-01-20, 00:00 authored by Vivek
S. Raut, Marion Jean, Nicolas Vanthuyne, Christian Roussel, Thierry Constantieux, Cyril Bressy, Xavier Bugaut, Damien Bonne, Jean RodriguezFor
the first time, enantiomerically enriched atropoisomeric furans
have been accessed using a central-to-axial chirality conversion strategy.
Hence, oxidation of the enantioenriched dihydrofuran precursors gave
rise to axially chiral furans with high enantiopurities accounting
from excellent conversion percentages (cp) in most cases.