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Electrical conduction is impaired in HSPB7 CKO hearts.

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posted on 2017-08-21, 17:39 authored by Wern-Chir Liao, Liang-Yi Juo, Yen-Ling Shih, Yen-Hui Chen, Yu-Ting Yan

(A and B) Annotated ECG curve of the HSPB7 CKO and control animals before (A) and 7 days after (B) the first tamoxifen injection. (C and D) Quantification of the ECG changes in HSPB7 CKO and control animals before (C) and 7 days after (D) the first tamoxifen administration. N = 5 per group. Data are presented as means ± SD. *, P < 0.05 **, P < 0.01 relative to the control. (E) Representative telemetric 2-lead ECG recording of a tamoxifen-treated HSPB7 CKO and control mice. Telemetry ECG recordings of lethal arrhythmias in HSPB7 CKO mice. n = 2 per group.

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