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Effects of TQ on NADH/NAD+ ratio in liver and soleus muscle.

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posted on 2017-09-26, 17:35 authored by Shpetim Karandrea, Huquan Yin, Xiaomei Liang, Angela L. Slitt, Emma A. Heart

(A) NADH/NAD+ ratio in liver. (B) NADH/NAD+ ratio in soleus muscle. p ≤ 0.05 when comparing (+) HFD and LFD, (*) HFD + TQ and HFD, and (#) LFD and LFD + TQ using independent t-tests. Results are means ± SEM (n = 8–10 mice per treatment group). LFD: low fat diet, HFD: high fat diet, TQ: thymoquinone.

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    NADactivationserum cholesterol levelsinsulin tolerance testsinsulin sensitivityphosphorylated SIRTSIRT -1-dependent pathways ThymoquinoneOGTTplant Nigella sativaameliorateAMPKtype 2 diabetesNADHSIRT -1-dependent pathwaysfasting blood glucoseinsulin-resistant HepG 2 cellsSIRT -1-dependent mechanismDIO mouse modelITTfasting insulin levelsTQphenotypeintracellular redox cyclingDiet-Induced Obesity miceMCP

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