Effect of immunobiotic bifidobacteria in antiviral immune response of porcine intestinal epithelial cell line (PIE cells).

<p>PIE cells were pre-treated with <i>B</i>. <i>infantis</i> MCC12 or <i>B</i>. <i>breve</i> MCC1274 for 48 hours, and then challenged with rotavirus OSU. The expression level of IFN-β, MxA, RNaseL, RIG-I, TLR3, A20, and cytokines (CXCL10, IL-6, IL-8, MCP-1) were quantified by RT-PCR after 6 and 12 hours. The results represent data from three independent experiments and are expressed as mean ± S.D. Asterisks indicate significant differences: <i>p</i> <0.05 (*), <i>p</i> <0.01 (**), and <i>p</i> < 0.001(***).</p>