Effect of Leptospira infection on extracellular matrix proteins in endothelial cells detected by immunofluorescence microscopy.

(A) collagen type IV, (B) decorin, and (C) laminin in HMEC-1 and HDLEC are shown in green. The nuclei are stained in blue for all panels. Scale bars represent 50 μm. Quantified signal intensity of the host protein is indicated in the right-hand graphs (mean +/- SD, p-value is indicated below each graph, the independent p-values shown as an asterisk are compared to uninfected cells).