Drychampones A–C: Three Meroterpenoids from <i>Dryopteris championii</i>

Three novel sesquiterpenoid-based meroterpenoids, drychampones A–C (<b>1</b>–<b>3</b>, respectively), were isolated from <i>Dryopteris championii</i>. Compounds <b>1</b> and <b>3</b> possessed a novel carbon skeleton which was constructed by an 11/6/6 ring system coupled with a pyronone moiety, and <b>1</b>–<b>3</b> were three racemates. Their structures and absolute configurations were elucidated by NMR, MS, and computational methods. The hypothetical biosynthetic pathways of these meroterpenoids and their antibacterial activities were also discussed.