Differentiation capacity of MSCs isolated by plastic adherence

2013-06-09T19:48:51Z (GMT) by Mark Hahnel
<p>This figure shows the published differentiation potential of bone marrow derived MSCs. Points i, ii, and iii show the classic defining differentiation potential of bone marrow derived MSCs down the chondrogenic, adipogenic and osteogenic lineages, respectively. Points iv, v and vi, show cell types which MSCs have been reported to differentiate into under set conditions in vitro, including neurons [1], cardiomyocytes [2] and hepatocytes [3].</p> <p> </p> <p>[1] Black IB, Woodbury D (2001) Adult rat and human bone marrow stromal stem cells differentiate into neurons. Blood Cells Mol Dis 27: 632-636.</p> <p>[2] Li XH, Yu XY, Deng CY, Lin QX, Shan ZX, et al. (2006) Differentiation of human bone marrow mesenchymal stem cells into cardiac phenotype in cardiomyocytes microenvironment. Acta Pharmacologica Sinica 27: 236-236.</p> <p>[3] Ishii K, Yoshida Y, Akechi Y, Sakabe T, Nishio R, et al. (2008) Hepatic differentiation of human bone marrow-derived mesenchymal stem cells by tetracycline-regulated hepatocyte nuclear factor 3beta. Hepatology 48: 597-606.</p>