ol702420x_si_002.pdf (3.43 MB)
Differentially Protected Benzenediboronic Acids: Divalent Cross-Coupling Modules for the Efficient Synthesis of Boron-Substituted Oligoarenes
journal contribution
posted on 2008-02-07, 00:00 authored by Hiroyoshi Noguchi, Takayuki Shioda, Chih-Ming Chou, Michinori SuginomeOn the basis of the boron-masking strategy, new divalent cross-coupling modules have been designed for the efficient synthesis of boron-substituted oligoarenes. The modules, i.e., monoprotected o-, m-, and p-benzenediboronic acid derivatives, undergo highly selective Suzuki−Miyaura coupling with sp2 iodides, bromides, chlorides, and triflates, affording coupling products in which the protected boronyl groups are
left intact.