Fig 8.TIF (406.02 kB)
Differentially-expressed immune-related and skin-enriched genes.
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posted on 2016-10-28, 17:30 authored by S. L. Rajasekhar Karna, Peter D’Arpa, Tsute Chen, Li-Wu Qian, Andrea B. Fourcaudot, Kazuyoshi Yamane, Ping Chen, Johnathan J. Abercrombie, Tao You, Kai P. Leung(A) The immune-related genes are from the Comprehensive List of Immune-Related Genes of The Immunology Database and Analysis Portal (ImmPort) ([20]; http://www.immport.org/immport-open/public/home/studySearch?searchTerm=SDY144). (B) The skin-enriched genes are comprised of 412 genes with elevated expression in skin compared to other tissue types (www.proteinatlas.org; [21]).
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skin-enriched coding gene expressioninoculating 10 6 bacteriaRNA-Seq Transcriptomic Responsesbiofilm infectionPseudomonas aeruginosa Acuteday -3 wounds24 hrsFull-Thickness Dermal Excision Woundspost-wounding day 3wound cells transitioningrabbit ear excisional wound modeldown-regulated genesRNU 6 pseudogenesncRNAcontrol woundsBiofilm Infection Pseudomonas aeruginosa infectionsgenome-wide gene expression
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