## Diagram of the MARzss method.

figure

posted on 17.04.2019 by Ningzhi Li, Linqing Li, Yan Zhang, Maria Ferraris Araneta, Christopher Johnson, Jun Shen#### figure

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The first part is the interleaved RF and gradient pulses (iPFG) train, where FA is the flip angle of each radio frequency (RF) pulse and G is the field gradient inserted between two RF pulses in the train. G is applied in the z direction. Water suppression is applied following the iPFG train. Steady state longitudinal magnetization is measured by a point-resolved spectroscopy (PRESS) sequence optimized for Glu detection at 7 Tesla.

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Monte Carlo simulationsincrease measurement precisionOptimized four-flip angle measurementsRFecho time-independent techniqueradio frequency pulse-drivenrelaxationMAR ZSS techniqueglutamatergic neuronsmatter-dominated medial prefrontal lobeintracellular environmentscan time2 x 2 x 2 cm 3 voxelglutamate T 2

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Monte Carlo simulationsincrease measurement precisionOptimized four-flip angle measurementsRFecho time-independent techniqueradio frequency pulse-drivenrelaxationMAR ZSS techniqueglutamatergic neuronsmatter-dominated medial prefrontal lobeintracellular environmentscan time2 x 2 x 2 cm 3 voxelglutamate T 2