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Determination of MTAP rs7023954 in cell lines and tissue samples.

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posted on 2016-08-01, 17:39 authored by Katharina Limm, Katja Dettmer, Jörg Reinders, Peter J. Oefner, Anja-Katrin Bosserhoff

The non-synonymous MTAP SNP c.G166A was genotyped by sequencing of cDNA that had been produced from total RNA extracted from both normal as well as primary (prim.) and metastatic (met.) melanoma cell lines and tissues. Distribution of the genotypes AA, AG, and GG is shown. A detailed description of the genotypes of the samples investigated is given in S1 Table.

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    Malignant Melanoma Deficiencycell linesprotein arginine methyltransferasesreceptor ADORA 2B Genetic association studiestranscription factor APmetastatic melanoma tissuescDNA amplicon sequencingtumor suppressive function.166GPRMTMTAPmethylthioadenosineSNP rs 7023954Methylthioadenosine Phosphorylase Polymorphism rs 7023954MTApolymorphism

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