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Data set - Causes and outcomes of sepsis in southeast Asia: a multinational multicentre cross-sectional study (NCT02157259)

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posted on 2016-12-22, 08:23 authored by Southeast Asian Infectious Clinical Research Network

This is an observational study to identify the etiology, management, and outcome of community-acquired sepsis and severe sepsis in children and adults in Southeast Asia. The study will take place in Thailand, Vietnam, and Indonesia, the partner countries of SEAICRN. Potential study patients will be any patients (both children and adults) who are presented at the hospital with community-acquired sepsis or severe sepsis and require hospitalization.


The fields contained in the database are as follows:

1. id: Unique identifier for each patient

2. country: The code of the country where each study hospital locates; 2 defines Thailand, 3 defines Vietnam and 4 defines Indonesia

3. site: The code of each study hospital

4. gender: The gender of patients

5. age_group_1: The age group of patients Children and Adults

6. age_group_2: The age group of patients; 1 mo - <1 year, ≥1 - <5 years, ≥5 - <18 years, ≥18 - <40 years, ≥40 - <60 years and ≥60 years old 

7. severe_sepsis: severe sepsis defined by Surviving Sepsis Campaign 2012 for adult patients, and by International paediatric  sepsis consensus conference 2005 for paediatric patients

8. severe_sofa: sepsis defined by having SOFA score more than or equal to 2 according to the 2014 task force for adult patients; missing value for paediatric patients

9. mortality28: 28-day mortality outcome. Mortality outcome was not available in 19 children and 5 adults who withdrew from the study prior to 28-day follow-up, and in another 13 children and 6 adults who could not be contacted for 28-day outcome.

10. group1_ari: 1 defines patients who had clinical presentations of acute respiratory infection

11. group2_dia: 1 defines patients who had clinical presentations of acute diarrhoea

12. group3_cns: 1 defines patients who had clinical presentations of acute CNS infection

13. group1_si: 1 defines patients who had clinical presentations of acute systematic infection


The following variables represent patients who had pathogens or diseases identified based on a set of diagnostic tests used as described in the main manuscript. 

14. any_pathogen: 1 defines patients who had at least one pathogen defined and 0 defines patients who had no pathogen defined

15. bact_01_typhi: 1 defines patients who had Salmonella typhi

16. bact_02_nontyphi: 1 defines patients who had non-typhi Salmonella

17. bact_11_ecoli: 1 defines patients who had Escherichia coli

18. bact_12_k_pneumo: 1 defines patients who had Klebsiella pneumoniae

19. bact_13_k_spp: 1 defines patients who had Klebsiella spp

20. bact_14_enterobacter: 1 defines patients who had Enterobacter spp

21. bact_15_proteus: 1 defines patients who had Proteus spp

22. bact_16_citrobacter: 1 defines patients who had Citrobacter spp

23. bact_17_shigella: 1 defines patients who had Shigella spp

24. bact_21_acineto: 1 defines patients who had Acinetobacter spp

25. bact_22_acrhomobacter: 1 defines patients who had Achromobacter spp

26. bact_23_aeromonas: 1 defines patients who had Aeromonas spp

27. bact_24_haemophillus: 1 defines patients who had Haemophilus spp

28. bact_25_campylobacter: 1 defines patients who had Campylobacter spp

29. bact_26_vibrio: 1 defines patients who had Vibrio spp

30. bact_27_pseudo: 1 defines patients who had Pseudomonas spp

31. bact_28_melioid: 1 defines patients who had Burkholderia pseudomallei

32. bact_31_legionella: 1 defines patients who had Legionella pneumophila 

33. bact_32_c_pneumonia: 1 defines patients who had Chlamydophila pneumoniae 

34. bact_33_c_psittaci: 1 defines patients who had Chlamydophila psittaci 

35. bact_34_bordetella: 1 defines patients who had Bordetella pertussis 

36. bact_35_neisseria: 1 defines patients who had Neisseria meningitidis

37. bact_36_other_gn: 1 defines patients who had other Gram-negative bacteria

38. bact_41_aerues: 1 defines patients who had Staphlococcus aureus

39. bact_42_strep_pneumo: 1 defines patients who had Streptococcus pneumoniae

40. bact_43_strep_suis: 1 defines patients who had Streptococcus suis

41. bact_44_strep_spp: 1 defines patients who had beta-hemolytic Streptococcus spp

42. bact_45_clostridium: 1 defines patients who had Clostridium difficile

43. bact_46_other_gp: 1 defines patients who had other Gram-positive bacteria

44. bact_51_lepto: 1 defines patients who had leptospirosis

45. bact_52_scrub: 1 defines patients who had scrub typhus

46. bact_53_murine: 1 defines patients who had murine typhus

47. bact_54_sfg: 1 defines patients who had spotted fever group 

48. bact_55_mycoplasma: 1 defines patients who had Mycoplasma pneumoniae

49. bact_56_tb: 1 defines patients who had Mycobacterium tuberculosis

50. virus_01_dengue: 1 defines patients who had Dengue virus

51. virus_02_hanta: 1 defines patients who had Hantavirus

52. virus_11_influenza: 1 defines patients who had Influenza virus

53. virus_12_adeno: 1 defines patients who had Adenovirus

54. virus_13_entero: 1 defines patients who had Enterovirus

55. virus_14_rsv: 1 defines patients who had Respiratory syncytial virus

56. virus_15_metapneumo: 1 defines patients who had Metapneumovirus 

57. virus_16_rhino: 1 defines patients who had Rhinovirus

58. virus_17_para: 1 defines patients who had Parainfluenza virus

59. virus_18_corona: 1 defines patients who had Coronavirus

60. virus_19_boca: 1 defines patients who had Bocavirus

61. virus_20_parecho: 1 defines patients who had Parechovirus

62. virus_21_hsv: 1 defines patients who had Herpes simplex virus

63. virus_22_vzv: 1 defines patients who had Varicella zoster virus

64. virus_23_mumps: 1 defines patients who had Mumps

65. virus_24_measles: 1 defines patients who had Measles

66. virus_25_rubella: 1 defines patients who had Rubella

67. virus_26_je: 1 defines patients who had Japanese encephalitis virus

68. virus_27_ebv: 1 defines patients who had Epstein-Barr virus

65. virus_28_cmv: 1 defines patients who had Cytomegalovirus

66. virus_31_astro: 1 defines patients who had Astrovirus

67. virus_32_noro: 1 defines patients who had Norovirus

68. virus_33_rota: 1 defines patients who had Rotavirus

69. fungus_01_candida: 1 defines patients who had Candida spp

70. fungus_02_cryptococcus: 1 defines patients who had Cryptococcus spp

71. parasite_01_malaria: 1 defines patients who had Malaria

72. parasite_02_cryptosporidium: 1 defines patients who had Cryptosporidium spp

73. parasite_03_strongyloid: 1 defines patients who had Stronglyloides stercoralis

74. parasite_04_e_histo: 1 defines patients who had Entamoeba histolytica


Funding

National Cancer Institute (HHSN261200800001E) and National Institute of Allergy and Infectious Diseases, National Institutes of Health, USA, and Wellcome Trust UK (106680/B/14/Z and 106698/B/14/Z)

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