ol6b00864_si_001.pdf (1.1 MB)
Curtius-like Rearrangement of an Iron–Nitrenoid Complex and Application in Biomimetic Synthesis of Bisindolylmethanes
journal contribution
posted on 2016-04-26, 17:51 authored by Dashan Li, Ting Wu, Kangjiang Liang, Chengfeng XiaA Curtius-like rearrangement of hydroxamates
to isocyanates was
discovered. This reaction was initiated from an iron(II)–nitrenoid
complex, which was generated by the iron(II)-catalyzed cleavage of
N–O bonds of functionalized hydroxamates. To demonstrate the
efficiency of this new Curtius-like rearrangement in synthetic chemistry,
a biomimetic strategy for the one-pot preparation of bisindolylmethanes
was developed.