ol7b01355_si_004.cif (474.24 kB)
Copper-Catalyzed Borylative Cyclization of in Situ Generated o‑Allenylaryl Nitriles with Bis(pinacolato)diboron
dataset
posted on 2017-06-26, 22:46 authored by Meijun Xiong, Xin Xie, Yuanhong LiuA Cu-catalyzed cascade
borylcupration/cyclization of in situ generated
allene-nitriles with B2pin2 has been developed,
which provides highly substituted 3-boryl-1-naphthylamines with
excellent regioselectivity and wide functional group compatibility.
It has been shown that, for the first time, the catalytically generated
allylcopper species can be captured by a cyano group from a normal
nitrile to furnish a carbocycle.