Fig 3.tif (811.71 kB)
Concentrations of oxylipins.
figure
posted on 2017-09-08, 18:05 authored by Annika I. Ostermann, Patrick Waindok, Moritz J. Schmidt, Cheng-Ying Chiu, Christopher Smyl, Nadine Rohwer, Karsten-H. Weylandt, Nils Helge SchebbPresented are concentrations of selected prostanoids, 5-LOX, 12-LOX, 15-LOX, CYP4 and CYP2 products of ARA, EPA and DHA as well as 18-HEPE in (A) plasma, (B) brain and (C) colon in transgenic fat-1 mice and wild type animals (WT-STD) on a sunflower oil based diet, as well as in wild type mice on the same diet enriched with EPA and DHA (WT-STD+n3) after 30 days of feeding. The lower limit of quantification (LLOQ) for the analyte is indicated in case it was not exceeded in >50% of the samples per group. Results of the statistical analyses for the comparison of oxylipins between the feeding groups after 30 days on the experimental diets are shown in S8 Table.