pcbi.1006016.g001.tif (2.4 MB)
Computational modeling schematics.
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posted on 2018-03-12, 17:26 authored by Michael Pablo, Samuel A. Ramirez, Timothy C. Elston(A) Molecules at the cell membrane and a thin slice of adjacent cytoplasm are simulated explicitly. Both compartments are modeled as 2D surface. (B) In the quasi-3D simulations, a well-stirred compartment representing bulk cytoplasm is added to approximate 3D effects. (C) Reaction scheme for a Turing-type model of Cdc42-dependent yeast polarity establishment from Goryachev and Polkhilko [4].
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polarity establishmentmembranefluctuations speed polarity establishmentmacroscopic rate constantsreaction-diffusion equation simulationsTuring pattern formation Polarity establishmentCdc 42 abundancesparticle-based simulationsyeast polarity establishmentyeast polarizationmoleculeRho GTPase Cdc 42model
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