gcoo_a_1512708_sm7428.doc (729.5 kB)
Complexation between nickel(II), cobalt(III) and hydrazones derived from pyridoxal 5′-phosphate and hydrazides of 2-,3-,4-pyridinecarboxylic acids in aqueous solution
Version 2 2018-11-26, 11:21
Version 1 2018-08-21, 06:46
journal contribution
posted on 2018-11-26, 11:21 authored by G. A. Gamov, M. N. Zavalishin, A. Y. Khokhlova, A. V. Gashnikova, V. V. Aleksandriiskii, V. A. SharninThe present work reports on stoichiometry, apparent stability constants of biologically relevant complexes of nickel(II), cobalt(III) with hydrazones derived from pyridoxal 5′-phosphate and hydrazides of 2-,3-,4-pyridinecarboxylic acids at pH 7.4, T = 25.0 °C, I = 0.25 determined using UV-Vis spectroscopy. The thermodynamic constants of some complexes formation (NiL, NiL2, NiL2H) were estimated. Cobalt(II) ion was found to be oxidized to cobalt(III). Co(II) and Co(III) form low-spin state complexes. Hydrazones binding ability (pL0.5) in the medium mimicking biological ones towards Ni(II) and Co(III) was estimated.