Comparison of maximum and minimum number of memory T cells formed in PB vaccines using different total antigen doses.

<p>Performance of PB protocols defined as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190940#pone.0190940.g004" target="_blank">Fig 4</a> for low, intermediate and high vaccine doses (the rest of parameter values are randomly chosen as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190940#pone.0190940.g004" target="_blank">Fig 4</a>). A) Each dot represents the maximum number of memory T cells for PB protocols with low and intermediate antigen doses. All the dots are above the line of equation <i>x</i> = <i>y</i> (dashed line), which implies that it is possible to produce more memory T cells with intermediate than with low antigen doses. B) Same as in A for intermediate vs high antigen doses. C,D) The maximum number of memory T cells produced with lower antigen doses can be larger than the minimum of memory T cells created when higher antigen doses are used.</p>