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Ciliatonoids A and B, Two Limonoids from Toona ciliata

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posted on 2016-05-26, 12:24 authored by Cui-Ping Liu, Guo-Cai Wang, Li-She Gan, Cheng-Hui Xu, Qun-Fang Liu, Jian Ding, Jian-Min Yue
Three new ring B-seco limonoids, ciliatonoids A–C (13), were isolated from Toona ciliate and structurally characterized by spectroscopic data, X-ray crystallography, and electronic circular dichroism analysis. Ciliatonoids A and B feature an unprecedented limonoid architecture, while ciliatonoid C belongs to a rare class of limonoids. Biological evaluation showed that compound 3 exhibited modest activities against the tested tumor cell lines.

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