Ciliatonoids A and B, Two Limonoids from <i>Toona ciliata</i>

Three new ring B-<i>seco</i> limonoids, ciliatonoids A–C (<b>1</b>–<b>3</b>), were isolated from <i>Toona ciliate</i> and structurally characterized by spectroscopic data, X-ray crystallography, and electronic circular dichroism analysis. Ciliatonoids A and B feature an unprecedented limonoid architecture, while ciliatonoid C belongs to a rare class of limonoids. Biological evaluation showed that compound <b>3</b> exhibited modest activities against the tested tumor cell lines.