Characteristics of different types of poly(A) sites

<p><b>Copyright information:</b></p><p>Taken from "A large-scale analysis of mRNA polyadenylation of human and mouse genes"</p><p>Nucleic Acids Research 2005;33(1):201-212.</p><p>Published online 12 Jan 2005</p><p>PMCID:PMC546146.</p><p>© 2005, the authors © </p> () Association of various PAS hexamers with different types of poly(A) sites [for detailed definition of nine types of poly(A) sites see and Results]. () Cluster analysis of PAS hexamers and poly(A) types. The grayscale heat map represents the percentages of usage of PAS hexamers in different poly(A) types, with the sum of all values for each poly(A) type set to 100%. The shade of a cell indicates its value, with darker ones corresponding to higher values. Two-way hierarchical clustering was conducted using Euclidean distance as the metric. () Percentage of the number of supporting cDNA/EST sequences for different types of poly(A) sites. The total number of supporting cDNA/EST sequences for a gene is set to 100%. () Distribution of the number of cleavage sites per poly(A) site for different types of poly(A) site. Different shades are used to represent the number of cleavage sites per poly(A) site.

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