Changes in the frequency of CD16⁺, CD56⁺ and CD16^-CD56^- NK cells expressing KIR3DL01 and KIR3DL05.

The percentages of CD16⁺, CD56⁺ and CD16^-CD56^- NK cells that are KIR3DL01⁺ (A), KIR3DL05⁺ (B) or KIR3DL01^-05^- (C) were monitored in peripheral blood. The mean and standard error (error bars) are shown for each subset. Significance values were calculated using a mixed effects model by comparing the results from acute (weeks 1–4) and chronic (weeks 6–24) infection to pre-infection (week 0) and are indicated with asterisks color-coded according to the corresponding NK cell population (p<0.05*, p<0.01**, p< 0.005*** & p<0.001****).