figshare
Browse
Fig 8.tif (1.51 MB)

Changes in cortical network activity induced by 7–8 cumulatively increasing concentrations of THIP in the absence and in the presence of 300 nM, 1 μM or 3 μM DS2.

Download (1.51 MB)
figure
posted on 2017-10-13, 17:31 authored by Benjamin M. Bader, Anne Steder, Anders Bue Klein, Bente Frølund, Olaf H. U. Schroeder, Anders A. Jensen

The heat maps to the left of the vertical hatched line present statistically significant changes in 40 activity parameters relative to native activity (no drug, 100%) (Student’s paired t-test, p≤0.05). The concentration-response relationships for the drug combinations at 10 selected activity parameters are given as mean ± S.E.M. relative to native activity (no drug, 100%). The heat maps to the right of the vertical hatched line present statistically significant changes in the 40 activity parameters between the activity induced by a specific THIP concentration co-applied with 300 nM, 1 μM or 3 μM DS2 relative to the activity induced by that specific THIP concentration on its own (100%) (Student’s paired t-test, p≤0.05).

History