C-intestinalis-full-tree.png (614.43 kB)
C. intestinalis Embryonic Differentiation Tree (1- to 112-cell stage)
figure
posted on 2016-02-12, 18:21 authored by Bradly AliceaBradly Alicea, Richard GordonRichard GordonDifferentiation tree (Gordon, 1999) of Ciona intestinalis (Ascidian, sea squirt) embryo from 1-cell to 112-cell stage (10 division events). Data from lineage trees and fate maps of Nishida (1994), Nishida and Stach (2014), and Tassy et.al (2010). Data for cell volume approximation from ANISEED database (http://www.aniseed.cnrs.fr/).
A division event occurs when a mother cell divides into two daughter cells. In rare instances, a mother cell only produces a single daughter cell. In this case, no size information is available for the daughter cell. According to the differentiation tree convention, smaller cells are placed to the left and larger cells are placed to the right.
Each cell is annotated with its standard nomenclature and a decimal value that describes the relative size of each daughter cell (e.g. smaller cell is 0.49, larger cell is 0.51).
References:
Gordon, R. 1999. The hierarchical genome and differentiation waves: Novel unification of development, genetics and evolution. World Scientific & Imperial College Press: Singapore & London.
Nishida, H. 1987 Cell lineage analysis in ascidian embryos by intracellular injection of a tracer enzyme. III. Up to the tissue restricted stage. Developmental Biology, 121, 526-541.
Nishida, H. and Stach, T. 2014 Cell lineages and fate maps in tunicates: conservation and modification. Zoological Science, 31, 645-652.
Tassy, O., Dauga, D., Daian, F., Sobral, D., Robin, F., et al. 2010. The aniseed database: Digital representation, formalization, and elucidation of a chordate developmental program. Genome Research, 20, 1459-1468.
