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Boxplot showing RASSF1A and DOK1 promoter methylation levels in non-cirrhotic, cirrhotic, and HCC tissues.

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posted on 2016-04-14, 22:43 authored by Oscar C. Araújo, Agatha S. Rosa, Arlete Fernandes, Christian Niel, Cristiane A. Villela-Nogueira, Vera Pannain, Natalia M. Araujo

Methylation levels were measured by pyrosequencing at different CpG sites and expressed as the mean percentage of all CpGs analyzed at a given gene. The statistical significance for DNA methylation level in non-cirrhotic and cirrhotic tissues was calculated by comparison to HCC samples.

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