Boron-Selective Biaryl Coupling Approach to Versatile Dibenzoxaborins and Application to Concise Synthesis of Defucogilvocarcin M

An efficient synthetic method for versatile dibenzoxaborins based on boron-selective Suzuki–Miyaura cross-coupling between <i>o</i>-borylphenols and aryl halides or triflates bearing a 1,8-diamino­naph­thalene-protected <i>o</i>-boryl group is reported. A short synthesis of defucogilvocarcin M was achieved using the proposed method in combination with several other boron-mediated transformations.