ol6b02610_si_001.pdf (10.1 MB)
Borane-Catalyzed Transfer Hydrogenations of Pyridines with Ammonia Borane
journal contribution
posted on 2016-09-28, 17:53 authored by Qiwen Zhou, Lanqiong Zhang, Wei Meng, Xiangqing Feng, Jing Yang, Haifeng DuWith the use of ammonia
borane as a hydrogen source, a borane catalyzed
metal-free transfer hydrogenation of pyridines was successfully realized
for the first time to furnish a variety of piperidines in 44–88%
yields with moderate to excellent cis-selectivities.
The ease in handling without requiring high pressure H2 makes this transfer hydrogenation practical and useful.